Randomized Clinical Trials in Stroke Research
نویسندگان
چکیده
منابع مشابه
Randomized Clinical Stroke Trials in 2007
This article reviews the randomized control trials (RCT's) that were published in 2007 of emerging pharmacotherapies in patients with acute (/= 12 weeks) stroke. A Medline search generated 22 RCT's in stroke in the year 2007 in the English language. These trials were primarily efficacy studies. These included the role of statins (an anti-lip...
متن کاملClinical Research Methodology 3: Randomized Controlled Trials.
Randomized assignment of treatment excludes reverse causation and selection bias and, in sufficiently large studies, effectively prevents confounding. Well-implemented blinding prevents measurement bias. Studies that include these protections are called randomized, blinded clinical trials and, when conducted with sufficient numbers of patients, provide the most valid results. Although conceptua...
متن کاملReview of the randomized clinical stroke rehabilitation trials in 2009
BACKGROUND Recent review of the available evidence on interventions for motor recovery after stroke, showed that improvements in recovery of arm function were seen for constraint-induced movement therapy, electromyographic biofeedback, mental practice with motor imagery, and robotics. Similar improvement in transfer ability or balance were seen with repetitive task training, biofeedback, and tr...
متن کاملBlindness in Randomized Controlled Trials
In combination with randomization, blinding or masking is an important factor in randomized controlled trials (RCTs), particularly in trials that assess therapeutic effects. Here an attempt is made to explain blindness and why it is important. In clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...
متن کاملClinical research in anaesthesia; randomized controlled trials or observational studies?
The new millennium has seen a consolidation of the difficulties in pursuing clinical research in anaesthesia. Anaesthesia is rarely seen as a specialty with a high academic profile [1]. Universities have been encouraged to concentrate their research effort on basic sciences, and research in clinical medicine has concentrated on those areas with a large impact on public health. In the UK cancer,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Investigative Medicine
سال: 2010
ISSN: 1081-5589,1708-8267
DOI: 10.2310/jim.0b013e3181c9b2d4